In Liverpool, following the launch of Sam Ryan's new company, the health secretary is assassinated. Sam summons the Lyell team with a plea to help investigate, but Nikki is unsure whether she can trust Sam, who seems to know more than she's revealing. Meanwhile, Jack and Nikki navigate their feelings for each other.

When a woman confesses to murdering her husband, the Lyell team must determine if all is as it seems. Meanwhile, Simone is shocked to be reunited with a detective from her childhood, and struggles to untangle her past.