Five-O must act swiftly when the daughter of a top neurosurgeon is kidnapped by Wo Fat in order to make the surgeon operate on a wounded U.S. undercover agent who is carrying secret information of use to the Chinese.

Dr. Lemira, an opposition leader for Greece, is living in exile in Hawaii, but Klaus Marberg is sent to assassinate him. His plan is to get himself shot and work his way into Dr. Lemira's confidence so he can kill him easily. McGarrett must work out this plot and save the day before it is too late.