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When a large amount of diseased rats are found on a boat with all the crew dead, Five-O must contend with an outbreak of bubonic plague.
Murders are being committed seemingly at random every six weeks, and McGarrett is at a loss to understand the motives for these crimes. However, a newspaper may hold the answer.
A family of white-trash mass killers arrive on Hawaii after wreaking a trail of devastation on the mainland, and McGarrett must catch them before they can do more damage on the islands.