While pursuing a fugitive who is using explosives as part of his revenge plan, Annie is injured and must turn to bounty hunter Ben Crowley (Eddie Cibrian) for help. With Annie on the shelf Jimmy must step up and lead the team, which puts Daisy's tactical experience to work in an effort to bring down the criminal, while Luke is forced to take a more pivotal part in the investigation.

When a vicious serial killer escapes prison and goes on a murder spree, Annie's only hope of catching him is through the cooperation of a jailed fugitive. The case takes a surprising turn when the squad realizes the killer's final target isn't who she appears to be.