With help from Kisuke Urahara, Ichigo and his friends arrive in Hueco Mundo to confront Quilge Opie and learn that their latest enemy are Quincies. Meanwhile, captains of the Thirteen Court Guard Squads are also coming to the same conclusion regarding the identity of the intruders who infiltrated the Soul Society to declare war against Head Captain Shigekuni Genryusai Yamamoto. After hearing the full report, Yamamoto orders all captains to prepare for the coming war, five days from now. Elsewhere, Yhwach, leader of the Wandenreich, plots his next move.

The Soul Reapers find temporary solace in learning that Ichigo is on his way to the Soul Society. But Quilge Opie uses his power to imprison Ichigo inside the Garganta. As he tries to break free, Ichigo begins to hear, through his Soul Phone, the screams of the Soul Reapers falling to the enemy's onslaught. Amid screams of terror and despair, a familiar voice reaches Ichigo, telling everyone not to give up. Meanwhile, having lost his Bankai to Äs Nödt, Byakuya Kuchiki orders Renji Abarai to figure out the enemy's ability while he acts as a decoy.