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The Bustice League - whose members all know one another through undertaking Tube and travel challenges in London - take on the regulars. Jeremy Vine hosts.
The Fylde Coasters, a group of friends who all live on the Fylde coast in the north-west of England, attempt to topple the Eggheads. Jeremy Vine hosts.
Hoping to wipe the smiles off the Eggheads' faces today are Albert CamOuse, who live near either the River Cam or the River Great Ouse in Cambridgeshire.