When the blood-smeared car of 27-year-old Stefanie Watson is found in a Maryland parking lot her family hold out hope she's still alive. But when a jawbone is dumped in a local neighborhood, a missing persons investigation becomes a murder.

When a Texas gas store owner, Subir Chatterjee, 58, is shot inside his check cashing booth in 2002, detectives suspect his killer is someone Subir knew. With the murderer's DNA in hand, one detective refuses to retire until the case is solved.