Nicole decides to get some revenge on Mary Cherry, using Harrison to do it. While she and Mary Cherry try to persuade Brooke to dump Josh and start dating George, in hopes that the new coupling will save's Brooke's plummeting popularity, and thus save their own as well.

Josh must attend the autopsy of a drunk driver. Sam confronts Harrison over his prescription drug abuse only to learn that he might be dying. Ms. Glass takes on Nicole's team in the homecoming race. Carmen reconnects with her mom.