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Lenny Henry joins Alex and Matt for The One Show Comic Relief special and Dermot O'Leary kicks off his 24-hour dance challenge for Red Nose Day live on the BBC piazza.
Phillip Schofield joins Alex and Matt to talk about his hypnotic new game show. Plus a look at what causes 'commuter rage' and how sniffer dogs are helping to conserve one of Britain's rarest and most elusive creatures.
Matt Baker and Angellica Bell are joined by Oscar-winning actor Sir Ben Kingsley, who talks about his new sci-fi film which co-stars Gillian Anderson. Plus a look at how one comedian is using her own experiences to break down the taboos surrounding disability. Andy Kershaw finds out why rail passengers on some routes in the north west of England are forced to use old converted buses. And Gyles Brandreth discovers how art lovers are snapping up original copies of famous paintings at a fraction of the usual cost.