Lola is still missing, Art is desperate. While Julien is still being held against his will in China, Isabelle tries to keep various impatient investors on board. She is once again thrown back on her talent for improvisation. During an important presentation by Isabelle, unexpected help arrives from a mysterious guest of Julien. A journalist stumbles upon more and more things that Rombauts Pharmaceuticals probably does not want to be public. Art is completely disoriented by Lola's disappearance and gets into psychological trouble. Isabelle's mother Riekje comes to the rescue.

Isabelle discovers the harsh side of the pharmaceutical industry. In her research into Aspergon, she encounters a lot of resistance, including from her direct colleagues. To her amazement, her son Art receives a ticket from his grandparents for his eighteenth birthday to travel around the world. He wants to leave soon. Ludo searches for the ideal place to grow the sea shell the northern quahog for the promising elixir. Julien does a DNA test to discover whether the Chinese girl Ming is really his daughter. Jerry Kwan tries to convince Julien to bring Rombauts Pharmaceuticals to the stock exchange.