Dr. Lyndsey joins Dr. Lee to help David, who is fearful that the lump on his jaw might be cancer. Carla has a large, mysterious bulge on her thigh that concerns Dr. Lee. James has over 70 skin tags that he wants removed so he can get his beach body back.

Dr. Lee asks Dr. Zoe to help double-team needle-shy Mary Ann's crusty skin. Isaiah's mom is concerned he is ignoring the large, growing lump over his lower spine. Maressa worries about the dangers of treating the oozing skin covering her ankles and body.