When a champagne bomb is delivered to Constantine, he and Celeste go on high alert to determine who wants him dead. Meanwhile, Nate turns to Grace after he accidentally jeopardizes a mobster's valuable racehorse. Back at Roosevelt Medical Center, Grace is tapped to treat Brett's estranged brother, Jack Hanson, following a severe cycling accident.

Grace's world crumbles as her family remains in jeopardy, the FBI closes in and Constantine reveals something that rocks her to the core. Meanwhile, longtime mobster Al Trapani becomes increasingly involved in Constantine's business, and Franco's secret leaks. As the walls begin to close in on Grace and the duality of her life cuts deeper than ever before, she makes a desperate attempt to settle her role in both worlds.