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A ray-gun makes Leonardo carefree and ignore his responsibilities. This leaves the Turtles defenseless and the city at the mercy of Maestro G Clef, a villain who destroys the city with music.
Bebop and Rocksteady use Krang's new Mutagen on Bebop's pet turtle Slash so he can do their housework for them. Slash runs away and is conned by an irritated entrepreneur into framing the TMNT.
When a power surge causes an arcade machine to release Tempestra, It's up to Leonardo to stop her digital wrath before she becomes dangerously powerful.