The Teenage Mutant Ninja Turtles are looking for some excitment. They soon find it when hoods start robbing fancy stores but only steal cufflinks! The turtles decide to investigate this and the only way to do so is to go as undercover crooks. After putting a competing gang "on ice", the turtles get the scoop on the cufflinks and learn which cufflink they really want which is a high explosive and so the turtles must keep the hoods, and Shredder, Rocksteady, and Bebop away from it.

A failed mutagen experiment results in an invasion of giant insects and arachnids in New York City.