With his parents out for the evening, home-alone Richie recovers from the Asiatic flu, waits for his friends to sneak him pizza and a movie, and surprises a burglar in the living room.

Having to drive the Cunningham family car and a run-in with a gang stack the odds against Richie and his buddies after Bag Zombrowski challenges them to come up with dates by midnight or walk through popular Arnold's parking lot in their underwear.