MTV's casting department demonstrates their mastery in being able to attract guest stars of the highest caliber in this episode, as Ashley Angel from O-Town visits Clone High and wins Cleo's heart. Meanwhile, Principal Scudworth chases a rascally skunk whose catch phrase is "Try and catch me, bitch!"

Jack Black guest stars in a trippy rock opera episode where the students get high from smoking raisins, and Gandhi has a bad trip where he is eaten by a live-action cat and encounters a two-headed Olsen Twins monster.