David Myers and Simon King embark on a 2,000-mile journey along the famous American road, taking them through eight different states, each with their own history, flavours and people. They begin by learning about Chicago's meatpacking industry, before moving on to small-town American, where they spend time with the Amish community, cooking together and learning about their different way of life. Their first leg ends in St Louis, where they try `concrete custard" - a treat so rich and thick it has to be served upside down.

On the third leg of their trip Dave and Si are on the trail of Oklahoma's famous beef. In Oklahoma City a classic T Bone steak is followed by a visit to the city's Vietnamese community to knock up Vietnam's beefy national dish - Pho.

After checking out El Reno's unique onion burger the Bikers hook up with a couple of fire crews who like to cook - especially brisket.

An organic sweet potato farm inspires the Bikers to make sweet potato brownies, before they finish this stretch on a cattle ranch with America's most iconic custodian of the land - the cowboy.