Pittsburgh's newest homicide detective Catherine Jensen is haunted by the disappearance of her brother years ago, and her parents have lost interest in finding him. However, Jensen must focus on her new job when a mummified corpse is found at a demolition site. She knows it is more than just an accident or random murder. She enlists the help of academic forensic psychologist Thomas Schaeffer who suggests a serial killer roams the city. When Catherine gets kidnapped by the killer, Schaeffer must think like him in order to solve the case and save her.

While the team continues to investigate the bludgeoning death at the dumpster and the suicide of a suspect, Catherine and Schaeffer must ask Judge Burgess to look at the suspect's sealed documents for clues. They travel to a rural farm where several adopted children, including the suicidal suspect, were raised. Meanwhile, the killer strikes again, killing a woman who had been questioned by the police.