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Jesse's insurance runs out and he gets transferred to County Hospital where he nearly dies of AIDS-related cardiac arrest; Becca discovers a haunting self-portrait of Jesse's that he doesn't remember painting.
Shortly after his 18th birthday, a feverish Jesse collapses in extreme pain at school and is rushed to the hospital, where he dreams of Becca. When he wakes up, he finds that his AIDS-Related Complex has progressed to AIDS.
A hospitalised Jesse is challenged to fight his disease by an irrepressible AIDS patient who refuses to passively accept his condition.