A powerful imp from the 5th dimension, named Mister Mxyzptlk, starts annoying Superman by appearing every 90 days to cause trouble and mischief. The comical villain gets equally aggravated because Superman repeatedly tricks him into saying, spelling or revealing his own name backwards, sending him back to the 5th dimension. Mister Mxyzptlk returns with a proposition for Superman—get him to say or spell his own name backwards twice in a row, and he promises to leave Superman alone forever.

Livewire escapes from prison, eager to punish Superman for placing her there. She teams up with Parasite to cause mayhem once again.