David Mitchell, Jimmy Carr, Charlie Brooker and Lauren Laverne broadcast live again. Guests include 'Freakonomics' co-author Stephen J Dubner, and David Mitchell chairs a panel debating whether protests work.

Lord Robert Winston and Conservative Dr Daniel Poulter MP discuss the NHS reforms with David Mitchell; Meanwhile Charlie Brooker looks at Gadaffi, Charlie Sheen's week and the iPad 2 launch; and Jimmy Carr attempts some product placement.