After a major setback in the Frozen Hearts case, Nancy asks Temperance for help with an occult approach to getting answers from a murder suspect. Meanwhile, the Bobbsey entanglement creates a world of trouble for Ace, and George has a long-overdue confrontation with someone from her past. 

While Nancy and her friends race to find the relic that could finally untangle George's soul from Odette Lamar's, Carson and Ryan are affected by a mystical substance that prompts a temporary return to the lowered inhibitions of adolescence.