A woman hires Rio and Wiley to rescue her daughter Carmen, who has been kidnapped by her father, a Buenaventuran drug kingpin.

After many years absence, physician Marco Ramos returns to Costa Perdida to care for his heart-sick mother. However, Marco's brother Reynaldo cannot forgive Marco for having abandoned him and their mother all those years ago, and wants to kill him in revenge. Rio and Wiley must try to prevent a bloodbath.