Sung is forced to meet with Risk Management's Fran Horowitz after refusing to apologize to the wife of a patient who died on his table. Ty and Michelle face a moral dilemma when a seemingly schizophrenic homeless man cannot provide the informed consent needed for life-saving surgery. Sydney and Lieberman can't leave work behind during their date. And Buck is forced to evaluate his callous behavior after being named in a lawsuit by malpractice attorney Mitch Tompkins.

Hooten's mentor, Dr. Arvin Wayne, walks into the wrong procedure on the wrong day, leading the surgeons at Chelsea General to question the cognitive abilities of one of the hospital's elder statesmen. When a top competitive swimmer suffers a seizure in the emergency room, Villanueva follows his gut – leading to a surprising diagnosis. Tina must perform a risky transvenous thrombolysis with Ty and Michelle's help. And Sydney implies that Lieberman might be a crummy doctor for missing the signs of bacterial endocarditis in a former patient.