During Monday's 311 conference, Hooten calls Dr. Stewart Delany to explain how a careless mistake killed Delany's young patient. But the outcome of the conference leaves the hospital's surgeons conflicted. Sydney and Villanueva operate on Keith Harriman, a young man with extensive injuries from an apparent suicide attempt. Sydney and Buck wonder about the resources wasted on those who cannot or do not want to be saved. And Mark Ridgeway returns, determined to make Ty and Tina pay for their adultery.

In the season finale, Hooten and Buck find themselves facing off in court against attorney Mitch Tompkins after a grieving son refuses to comply with his mother's final wishes. Sydney's outrage over the health of a morbidly obese 16-year-old boy further strains her relationship with Lieberman. And a seemingly harmless patient puts one of Chelsea General's own in grave danger.