As the dust settles in Fort Collins, Josh gets word that a new federal crackdown could close one of his dispensaries in Denver. Meanwhile, Sergeant Jim Gerhardt discovers an illegal basement grow while investigating the cause of a house fire, and Josh receives word that his grow has been robbed.

Pot entrepreneur Josh Stanley faces a huge challenge in persuading Colorado to finance scientific R and D into cannabis as medicine, and the Denver Police Department conducts undercover Craigslist operations to try to keep a lid on the expanding black market in marijuana. And then there's Brittany Wagoner, Miss High Times 2010, who is out to prove that she's more than just a pretty face in what she sees as the predominantly male world of marijuana.