A derelict is found dead in a New York alley. At first glance, it appears that the dead man succumbed to alcoholism, but the other clues--including several conspicuously missing items--don't add up. Jessica Fletcher teams with ulcerated NYPD lieutenant Hanratty to make sense of the case, leading both sleuths to a group of disreputable doctors.

Jessica travels to Moscow to attend the International Artists and Writers Conference. No sooner has she arrived that someone steals her purse--and when the police catch up with the thief, they find a role of microfilm amongst Jessica's belongings. Immediately, the KGB accuses our heroine of being a spy--which doesn't anger her quite as much as the subsequent murder accusation leveled at an old friend.