Having managed to secretly inform his men of the departure date of the train carrying him to Alcatraz, Al Capone continues to work om his escape. The plan is to free Capone when the train stops for 5 minutes in the northern California community of Cloverville. Capone's men arrive the day before the snatch and basically take over the town at gunpoint. Ness and his men are soon on to them however and manage to enter the town. Needless to say, Capone ends up in Alcatraz.

With the imprisonment of Al Capone for tax evasion, Frank Nitti has taken over the operation of the organization but that isn't stopping others from trying to muscle their way in. Arnie Seeger in particular thinks he has the opportunity to create a national crime syndicate and partners with St. Louis mobster Joe Kulak to make it happen. They plan on inviting key mobsters from across the country to a conference in Chicago. Into this mix comes a recently released small-time criminal, Maxie Schram.