Jamie and Eddie suspect foul play when they respond to a distress call from a woman having an allergic reaction to her lifesaving medication, and learn that her husband is an EMT assigned to take her call, but didn't respond. Also, Erin learns that a man she convicted years earlier might be innocent of the crime, and Frank handles a PR crisis in his department when an exposé on Garrett Moore is published.

Erin faces off against her ex-husband in court when he represents the person she is attempting to convict of murder; a mother accuses the NYPD of being negligent in solving her son's murder; Jamie rides with a new partner.