Danny and Baez investigate the murder of a single mother whose ex-husband has a history of violence. Also, Frank deals with the fallout when Mayor Dutton eliminates solitary confinement in prisons, and Jamie's efforts to save a young woman who overdosed on drugs has unexpected consequences.

A case turns personal for Danny when he works to protect a nurse, Faith Madson, from her violent ex-boyfriend. Also, Shelly Wayne, an acquaintance of Frank's, comes to him with a theory regarding the death of an inmate, and Jamie and Eddie help deliver a baby.