Danny and Baez investigate a murder attempt against a celebrated fertility doctor with a seemingly pristine reputation. Also, Eddie is called to intervene in a Reagan family matter involving Danny's boys; Erin helps Anthony find justice after a date night goes wrong; and Frank ties up loose ends with an old friend.

Things get personal for Danny when Luis Delgado, the drug cartel hitman responsible for torching his house, resurfaces. Also, an attack on an officer in the line of duty directly impacts a member of Frank's team; Eddie reluctantly introduces Jamie to her mother, Lena; and Erin deals with the consequences of her new role as boss.