Protests over immigration raids pop up across the United States. Also, Defense Secretary Pete Hegseth struggles to clarify the Trump administration's position on Russia. And House Republicans are forced to again vote for the Medicaid cuts in of Donald Trump's budget bill. Sen. Adam Schiff, Rep. Jason Crow, and Rep. Paul Tonko join Lawrence O'Donnell.

Outrage grows over the handcuffing of Senator Alex Padilla. Also, "No Kings" protests are expected in over 2,000 cities on Saturday. Plus, Iran launches retaliatory missiles into Israel. And Trump policies disrupt life on the U.S.-Canada border. M. Gessen, Ruth Ben-Ghiat, David Rothkopf, Sylvie Boudreau, and Rep. Becca Balint join Ali Velshi.