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Still reeling from the death of informant Anna, Voight faces a new threat as he tries to keep the neighborhood clean. New wrinkles develop in the Upton, Halstead and Voight dynamic. The team gets a new chief.
When a convicted murderer hijacks a prison van, the team scrambles to find him and the abducted prison guard before it's too late. Burgess questions Ruzek's motives in a case, creating tension between the two.