When Brian calls in sick for a day off from the FBI, the CIA abducts him from home to borrow his NZT-enhanced capabilities for a black ops mission. As the operation becomes increasingly dangerous, Brian finds himself without FBI support in a situation that's spiraling out of control.

Brian offers to use NZT to capture the FBI's "Ten Most Wanted" criminals in two weeks, in exchange for Naz giving him his own personal work "headquarters" at the agency. Also, the secretive nature of Brian's new life working for the Bureau creates a rift between him and his father.