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A man from the future visits the boys and reveals himself as Kaz twenty-five years from now. Future Kaz warns the boys of an evil villain wreaking havoc on the future.
Skylar realizes her powers are greater than the Annihilator's and no longer wants to take orders from him.
Oliver, Skylar, Alan and Gus leave Mighty Med to work on a school project together, and Kaz is left alone at Mighty Med while a rare and dangerous alien bug is on the loose.