Huff grapples with the dangers of psychiatry when a young, eager and attractive pharmaceutical rep does her best to persuade him to aggressively prescribe. But Beth discovers an item in Izzy's closet that may be alarming enough to distract him from his flirtation. Over in the land of Russell, Huff's lawyer friend may be the victim of federal surveillance or simply the victim of his own paranoia.

As Beth prepares for the arrival of her gravely ill mother, the rift between she and Huff escalates, putting them both in a position we've never seen them in before. With Huff realizing that there's no way he'll ever be able to "put the toothpaste back into the tube", Russell confronts the horrifying possibility that he may have unintentionally started a family during a recent ecstasy binge.