SuperMansion: War On Christmas focuses on a dysfunctional group of self-righteous superheroes, The League of Freedom, who can't agree on anything, but must band together to save Christmas when an interstellar imp, Mr. Skibumpers, unleashes a real-life Santa Claus who experiences an existential crisis and runs amok. Ultimately, the team comes to understand that their differences of opinion are what the holiday spirit is all about.

To boost the League's dismal approval ratings, Rex seeks the help of TV host Portia Jones (Yvette Nicole Brown) at Champston University. As League members descend on the world of academia, each finds their college niche, but in the process unleash a campus villain.