Cooch and Liplor ride the success of their TV show while Saturn and Ranger join the crew. Titanium Rex and Dr. Devizo have unfinished business on an island where Sgt. Agony has identified a mysterious supervillian, whose powers combine with a tropical storm to render Devizo and Rex vulnerable.

Fearing that Lex's insectine influences have made The League a threat, Sgt. Agony imprisons the heroes beneath the mansion. As yet uncaptured, Black Saturn assembles a team to bust his roommates from their confinement. Lex remains on the run, fighting to contain her terrifying insect nature.