When the School of Friendship is closed by Chancellor Neighsay of the Equine Educational Association, Twilight Sparkle must reunite her students, inspire her friends and buck the rules to stand up for what she knows is right for every creature, pony or not.

When Fluttershy is the only pony available to look after the Manehattan boutique while Rarity is away, she takes on a series of characters to cope with the intimidating clientele and learns that she was already the best pony for the job just by being herself.