Heavenly and Lisa Nicole embark on a new business venture, but their collaboration quickly turns ugly, when Heavenly shares her true feelings about Lisa Nicole's marriage. Simone is back at work after her emotional trip to Nashville with a transgender patient who wants gender reassignment surgery. Meanwhile, Jackie's topless charity photo shoot gets out of control causing her to expose a very different side of her personality.

After their huge argument at Toya's Prom Party, Mariah and Quad's friendship is on shaky ground. Quad is planning a birthday bash for Dr. G and doesn't want Mariah to bring her drama to the party, so she takes "extra" precautions. Toya faces the hard truth she can no longer afford the lifestyle she wants but when it's time to make changes she gets cold feet. Lisa's antics put Heavenly's patience to the test as they plan for their upcoming conference.