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Meredith, rattled by the latest events, tries to figure out what to do about Derek. Meanwhile, Owen is shocked when his mother is admitted to the hospital.
Patient's condition sparks a conversation between Richard and Maggie about Alzheimer's disease; April and Jackson struggle to return to their normal lives and Arizona is faced with the reality that Callie is moving on. Meanwhile, Meredith reveals her biggest fears about Derek.
School field trip to the hospital takes a dramatic turn when the kids witness two injured cops enter the emergency room. Meanwhile, Stephanie sets her eyes on one of the chaperones, Callie operates on the leg of the police captain and Amelia must face her feelings for Owen.
Primetime television's most riveting hour hits new heights as secrets of the past come to light and critical choices shape the future. Relationships are in turmoil as things between Callie and Arizon cool -- and Owen and Amelia's romance ignites. April and Jackson face a heartbreaking tragedy. Meanwhile, Meredith makes a stunning family discovery as opportunities pull Derek further away. And Maggie's shocking announcement proves that blood is thicker than water.