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Richard throws everyone for a loop when he switches the resident and attending pairings, and Arizona takes a huge risk on a woman who is pregnant with quadruplets. Meanwhile, April is faced with a difficult decision.
Meredith, Bailey, Jackson, Callie and Jo travel to a military hospital to perform an extraordinary and extremely risky surgery on a veteran with an advanced tumor. Meanwhile back at Grey Sloan, Andrew is tired of being Maggie's worst kept secret; Ben makes an impulsive surgical decision; and a team of cheerleaders wreak havoc in the ER.
Jackson learns about April's pregnancy, while Alex and the team of doctors handles an hours-long triple-organ transplant surgery. Meredith considers dating again, and Andrew insists on not receiving special treatment after he and Maggie go public.
Meredith struggles to deal with all her responsibilities after Amelia moves in with her, while Miranda begins life as the new Chief of Surgery.