A young boy is admitted to Grey Sloan Memorial and his case has a profound impact on the doctors. Meanwhile, April is faced with a surprising patient, and Jo continues to deal with her estranged husband.

April is in charge of the new Grey Sloan Surgical Innovation Contest, and the doctors are eager to start their projects. Meanwhile, Catherine's old friend has a shocking idea for Catherine and Jackson; and Meredith treats a returning patient who inspires her project.