Maggie and Jackson are enjoying spending time together, but he must turn his concentration toward the groundbreaking vaginoplasty surgery he has scheduled with Catherine and Richard. Meanwhile, Meredith and Jo hit a roadblock with their contest submission, so Jo helps Bailey with an incoming trauma patient who used to be an astronaut.

Amelia, Koracick and DeLuca perform a risky, groundbreaking procedure using ultrasound waves to remove a young patient's brain tumor. Meanwhile, Meredith and Jo work with different polymers to try to salvage their project submission; and Richard's AA sponsor is admitted to Grey Sloan with a DNR.