Meredith and Dr. Shepherd have to use more than medicine when a young woman's traditionalist, religious father forbids her to have a life-saving operation. Meanwhile, George and Alex are forced to perform surgery under less than ideal conditions in an attempt to save a patient's life, and its decision time for Derek and the two women in his life.

Gossip is all the rage at Seattle Grace with Meredith feeling the brunt of it as a pregnant man comes into SGH and a heart spontaneously combusts!