Following a difficult case, the team faces the complexities of medical ethics. Meanwhile, Bailey continues to navigate her working relationship with Ben, while a group of college students on a scavenger hunt causes chaos around the hospital.

Amelia and Simone attempt to perform a high-stakes and groundbreaking brain surgery. Teddy and Bailey attend a medical conference and run into Dr. Cass Beckman. Meanwhile, Jo struggles with her irritation toward a younger