In this Meredith & Cristina-centric episode, the two friends continue to cope with life after the plane crash and their ever-growing responsibilities at their respective hospitals. As Meredith juggles taking care of Zola with a case that hits close to home, Cristina assists Dr. Thomas on a challenging heart surgery.

Cristina and Owen continue to figure out their relationship amidst the pending lawsuit; and Bailey argues with Ben over plans for their upcoming nuptials. Meanwhile, Callie recruits Jackson to help find a solution to Derek's hand, but he is preoccupied by a shocking situation with April.