When an undercover CIA agent is kidnapped by a band of separatists in Uzbekistan, the task force sets a rescue mission in motion. Red informs Agents Keen and Ressler that they are up against "Ruslan Denisov," a very dangerous past associate.

When Liz learns of a serial killer known as "The Deer Hunter" who tracks his victims like prey, Red helps the task force search for the killer. Meanwhile, the local DC police suspect the city Harbormaster was murdered as Liz struggles to keep her secret from unraveling.