The Helicarrier is commandeered by Zodiac, an elite criminal organization led by Scorpio, who imprison Nick Fury, hack into S.H.I.E.L.D.'s database and set the ship to self-destruct. Spider-Man is left as the only person who can save Fury and stop Zodiac before they obtain valuable data and the ship self-destructs over New York City.

When Midtown High School has a snow day, Agent Coulson orders Spider-Man and his team to report to a S.H.I.E.L.D. Arctic base for winter survival training. They instead go against their orders and sneak off to a deserted tropical island (which Nova finds on the S.H.I.E.L.D. database) for a vacation. However, while the island seems like a beautiful paradise, something sinister is lurking in the sand and does not want its new "play-mates" to leave again.