Spider-Man and his team travel to the moon to save the son of Spidey's greatest critic, J. Jonah Jameson -- but a bizarre threat awaits them on the lunar surface.

While looking for Thor who is missing in action, Spider-Man's team is shrunk into super-small versions of themselves by one of Loki's tricks. Nick Fury has Spider-Man's team placed in the Helicarrier's D.A.Y.C.A.R.E. area, but with Thor also having been shrunk, Spider-Man's team must find a way to help Thor fight Loki and the Destroyer Armor and return to normal size.